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Joint Fluid Analysis

Definition, Purpose, Precautions, Description, Preparation, Aftercare, Risks, Normal results, Abnormal results



Joint fluid analysis, also called synovial fluid analysis, or arthrocentesis, is a procedure used to assess joint-related abnormalities, such as in the knee or elbow.

Purpose

The purpose of a joint fluid analysis is to identify the cause of swelling in the joints, to relieve pain and distention from fluid accumulation in the joint, and to diagnose certain types of arthritis and inflammatory joint diseases. The test is also a method to determine whether an infection, either bacterial or fungal, exists within the joint.



Precautions

Joint fluid analysis should not be performed on any patient who is uncooperative, especially if the patient cannot or will not keep the joint immobile throughout the procedure. Patients with certain infections should be excluded from the procedure, particularly those who have a local infection along the proposed needle track. The joint space should be accessible. Therefore, a poorly accessible joint space, such as in hip aspiration in an obese patient, should not be subject to this procedure.

Description

The test is also called arthrocentesis, joint tap, and closed joint aspiration. Normal synovial fluid is a clear or pale-yellow fluid found in small amounts in joints, bursae (fluid-filled sac found on points of friction, like joints), and tendon sheaths. The procedure is done by passing a needle into a joint space and sucking out (aspirating) synovial fluid for diagnostic analysis. When the sample is sent to the laboratory, the fluid is analyzed for color, clarity, quantity, and chemical composition. It is also examined microscopically to check for the presence of bacteria and other cells.

The procedure takes about 10 minutes. Prior to the procedure, any risks that are involved should be explained to the patient. No intravenous pain medications or sedatives are required, although the patient will be given a local anesthetic.

The patient is asked to lie on their back and remain relaxed. The local anesthetic, typically an injection of lidocaine, is then administered. The clinician is usually seated next to the patient. Then the clinician marks exactly where the needle is to enter. As the needle enters the joint, a "pop" may be felt or heard. This is normal. Correct placement of the needle in the joint space is normally painless. At this point, the clinician slowly drains some of the fluid into the syringe. The needle is then withdrawn and adhesive tape is placed over the needle site.

Preparation

Glucose, or sugar, in the joint can be a signal of arthritis. If the clinician will be doing a glucose test, the patient will be asked to fast for 6-12 hours preceding the procedure. If not, there is no special preparation required for a joint fluid analysis.

Aftercare

Some post-procedural pain may be experienced. For this reason, the patient should arrange to be driven home by someone else. Aftercare of the joints will depend on the results of the analysis.

Risks

While joint fluid analysis is generally a safe procedure, especially when performed on a large, easily accessible joint, such as the knee, some risks are possible. Some of the complications to the procedure, although rare, include infection at the site of the needle stick, an accumulation of blood (hematoma) formation, local pain, injury to cartilage, tendon rupture, and nerve damage.

Normal results

The results of a normal joint fluid analysis include fluid of a clear or pale-yellow color and the absence of bacteria, fungus, and other cells, such as white blood cells.

Abnormal results

The results of an abnormal joint fluid analysis include fluid that is turbid, or cloudy. Also, white blood cells and other blood cells may be found, from which the clinician can make a diagnosis and arrive at a treatment for the joint problem. An abnormal result can indicate an infection caused by a bacteria, or tuberculosis. Or, there might be inflammation that is caused by gout, rheumatoid arthritis, or osteoarthritis.

Resources

BOOKS

Arnold, William J., and Robert W. Ike. "Specialized Procedures in the Management of Patients with Rheumatic Diseases." In Cecil Textbook of Medicine, ed. James B. Wyngaarden, et al. Philadelphia: W. B. Saunders Co., 1996.

Ron Gasbarro, PharmD

KEY TERMS


Aspirate—The removal by suction of a fluid from a body cavity using a needle.

Bursae—A closed sac lined with a synovial membrane and filled with fluid, usually found in areas subject to friction, such as where a tendon passes over a bone.

Hematoma—A localized mass of blood that is confined within an organ or tissue.

Synovial fluid—A transparent lubricating fluid secreted in a sac to protect an area where a tendon passes over a bone.

Additional topics

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