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Arteriovenous Fistula

Definition, Description, Causes and symptoms, Diagnosis, Treatment



An arteriovenous fistula is an abnormal channel or passage between an artery and a vein.

Description

An arteriovenous fistula is a disruption of the normal blood flow pattern. Normally, oxygenated blood flows to the tissue through arteries and capillaries. Following the release of oxygen in the tissues, the blood returns to the heart in veins. An arteriovenous fistula is an abnormal connection of an artery and a vein. The blood bypasses the capillaries and tissues, and returns to the heart. Arterial blood has a higher blood pressure than veins and causes swelling of veins involved in a fistula. Although both the artery and the vein retain their normal connections, the new opening between the two will cause some arterial blood to shunt into the vein because of the blood pressure difference.



Causes and symptoms

There are two types of arteriovenous fistulas, congenital and acquired. A congenital arteriovenous fistula is one that formed during fetal development. It is a birth defect.

In congenital fistulas, blood vessels of the lower extremity are more frequently involved than other areas of the body. Congenital fistulas are not common. An acquired arteriovenous fistula is one that develops after a person is born. It usually occurs when an artery and vein that are side-by-side are damaged and the healing process results in the two becoming linked. After catheterizations, arteriovenous fistulas may occur as a complication of the arterial puncture in the leg or arm. Fistulas also form without apparent cause. In the case of patients on hemodialysis, physicians perform surgery to create a fistula. These patients receive many needle sticks to flush their blood through dialysis machines and for routine blood analysis testing. The veins used may scar and become difficult to use. Surgery is used to connect an artery and vein so that arterial blood pressure and flow rate widens the vein and decreases the chance of blood clots forming inside the vein.

The main symptoms of arteriovenous fistulas near the surface of the skin are bulging and discolored veins. In some cases, the bulging veins can be mistaken for varicose veins. Other fistulas can cause more serious problems depending on their location and the blood vessels involved.

Diagnosis

Using a stethoscope, a physician can detect the sound of a pulse in the affected vein (bruit). The sound is a distinctive to-and-fro sound. Dye into the blood can be tracked by x ray to confirm the presence of a fistula.

Treatment

Small arteriovenous fistulas can be corrected by surgery. Fistulas in the brain or eye are very difficult to treat. If surgery is not possible or very difficult, injection therapy may be used. Injection therapy is the injection of substances that cause the blood to clot at the site of the injection. In the case of an arteriovenous fistula, the blood clot should stop the passage of blood from the artery to the vein. Surgery is usually used to correct acquired fistulas once they are diagnosed.

Resources

BOOKS

Alexander, R. W., R. C. Schlant, and V. Fuster, eds. The Heart. 9th ed. New York: McGraw-Hill, 1998.

Berkow, Robert, ed. Merck Manual of Medical Information. Whitehouse Station, NJ: Merck Research Laboratories, 1997.

Braunwald, E. Heart Disease. Philadelphia: W. B. Saunders Co., 1997.

John T. Lohr, PhD

KEY TERMS


Congenital—Present at the time of birth.

Additional topics

Health and Medicine EncyclopediaHealth and Medicine Encyclopedia - Vol 3